The NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules (NIH Guidelines) detail safety practices and containment procedures for basic and clinical research involving recombinant or synthetic nucleic acid molecules, including the creation and use of organisms and viruses containing recombinant or synthetic nucleic acid molecules. The BMBL (Biosafety in Microbiological & Biomedical Laboratories) includes biosafety information related to research involving recombinant or synthetic nucleic acid molecules.

Biosafety in Microbiological and Biomedical Laboratories 5th Edition (pdf)

NIH Guidelines (pdf)

NIH Guidelines (html)